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The prevalence of BRCA1 and BRCA2 mutations in Korean women with breast cancer at a young age was high. One of our major research interests is to define BCL-2 family function in the cellular decision to induce mitochondrial outer membrane permeabilization and apoptosis.

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Footshock stress also resulted in a slight but significant increase in DOPAC levels in the olfactory tubercles. How is social dysfunction primarily assessed in current research? Fast (4,3)D GFT-TS NMR for NOESY of small to medium-sized proteins.

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The use of in-office, orthopaedist-performed ultrasound of the shoulder to evaluate and manage rotator cuff disorders. Later studies showed that retroviral integration in the MDS1/EVI1 locus results in the emergence of a non-malignant dominant hematopoietic stem cell clone in non-susceptible mice strains, in non-human primates, and in patients, suggesting that a gene encoded by the locus could affect the self-renewal potential of a cell. To investigate whether the prevalence of attention-deficit/hyperactivity disorder (ADHD) is higher in children presenting with nasal and aural foreign bodies than in the control group.

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In recent years, internet addiction disorder (IAD) has become more prevalent worldwide and the recognition of its devastating impact on the users and society has rapidly increased. Cell-to-cell virus spread and the proliferation of latently infected cells, for which gp150 was dispensable, therefore appeared to be the major route of virus propagation in an infected host. We performed Fine and Gray regression, and Cox multivariable analysis to determine whether an increasing prostate specific antigen nadir was associated with prostate cancer specific and all cause mortality, adjusting for treatment, age, Adult Comorbidity Evaluation 27 score and cancer prognostic factors.

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In vitro drug release was also investigated with simulated biological fluids and the kinetics was studied under different pH conditions. The effect of the course of pregnancy and labor on the proteinogram of newborn infants In this article, information about the cellular, genetic and clinical factors contributing to antifungal-drug resistance, and their diagnostic and epidemiologic characteristics are reviewed. Intrathecal injections of arginine vasopressin (AVP) (3 pmol) into the lower thoracic region in rats produced consistent, dose-dependent antidiuretic responses accompanied by elevated urine osmolality.

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Childhood obesity is emerging as a considerable public health problem with no clear antidote. In vivo, different clinical features and gas expansion were observed after the injection of PFCLs saturated with CO(2) or SF(6). Identification of clinical features of lymphoma-associated hemophagocytic syndrome (LAHS): an analysis of 69 patients with hemophagocytic syndrome from a single-center in central region of China. Parallel solution-phase synthesis of (Z)-3-(arylamino)-2,3-dehydroalanine derivatives and solid-phase synthesis of fused pyrimidones. High-fat diet and age-dependent effects on enteric glial cell populations of mouse small intestine.

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Part II: Reconstruction of multienzyme pathways in plants and microbes. Hepatitis B assays in serum, plasma and whole blood on filter paper. Using acetone and trichloroacetic Acid to concentrate proteins and remove interfering substances. The evolution of active vibrissal sensing in mammals: evidence from vibrissal musculature and function in the marsupial opossum Monodelphis domestica.

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Affective-cognitive meta-bases versus structural bases of attitudes predict processing interest versus efficiency. Overhead canopies in giant reed stands and native riparian forests reduce daily high temperature, which was the best abiotic predictor of oviposition by engorged females.

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Different types of Metolose polymers were compared considering their thermoresponsive behavior. Lanthionine synthetase component C-like protein 1 (LanCL1) was identified as a potential intracellular target of R8 by using a photo-crosslinking assay that utilized a phenyl-trifluoromethyl diazirine moiety and peptide mass fingerprinting. Further work is needed to determine whether tailoring the processing to the characteristics of the individual hearing-impaired listener is beneficial. In contrast, electroconvulsive seizures resulted in brief demyelination and a faster recovery time course. We have therefore studied anti-streptococcal antibodies (ASO and ADNAseB) prospectively.

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DTI-based metrics are sensitive to regional structural changes in the contralesional hemisphere during stroke recovery. Platelets may participate in each of these steps and thus play a role in the pathogenesis of tumor cell metastasis.

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Other factors are fundamental conceptual structures such as the dream of the regenerative body as well as the view of the body as an object of utility and an object of value. In the top of the space the peritoneum was incised under laparoscopic control, which allowed passage of the forceps from the perineum and enabled descent of the isolated sigmoid segment. The 25 exposed subjects averaged 4.3 neurobehavioral abnormalities, significantly different from 2.5 for local controls and 2.3 for Tennessee controls. Uptake of noradrenaline by the adrenergic fibers of the submaxillary and sublingual glands of the rat. Homologous NF-YC2 subunit from Arabidopsis and tobacco is activated by photooxidative stress and induces flowering.

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The perivascular infiltrates of the rheumatoid synovium were examined in the electron microscope. Implantation along needle tract may lead to change of stage of the tumor, converting a resectable tumor into an inoperable one. Mannan transglycosylase: a novel enzyme activity in cell walls of higher plants. Regeneration of the crystalline lens in anuran amphibia in the postembryonal stage. Abdominal aortic aneurysm imaging with 3-D ultrasound: 3-D-based maximum diameter measurement and volume quantification.

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Methemoglobinemia in children as a differential diagnosis of cyanosis It was shown that the differential AChE staining of the amygdala could be used to accurately delineate amygdaloid subdivisions macroscopically. Tracheal aspirate samples and serum were obtained from all infants on the first day of admittance for evaluation of pro- and anti-inflammatory cytokine levels using ELISA.

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The recent discovery of numerous human short open reading frame (sORF)-encoded polypeptides (SEPs) has raised important questions about the functional roles of these molecules in cells. This study indicates that the NA-ALCP is psychometrically robust, easily understood and one-quarter the length of the original version.

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By taking advantage of the DNA-encoding strategy, aqueous AgNCs were used as signal transducers to convert DNA inputs into fluorescence outputs for the construction of various DNA-based logic gates (AND, OR, INHIBIT, XOR, NOR, XNOR, NAND, and a sequential logic gate). Prospective evaluation of coagulation activation in pregnant women receiving low-molecular weight heparin. Effect of vitamin a on development of the central nervous system.

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Determining the contributions of caspase-2, caspase-8 and effector caspases to intracellular VDVADase activities during apoptosis initiation and execution. A similar, corelike structure is frequently noted clinically in some drusen-related conditions. To study trends in the main indicators of health, medical practices and risk factors in France. Influence of pregnancy on neuromyelitis optica spectrum disorder. Reversal of the nephrotic syndrome has been reported, but the mechanisms of this effect are unclear.

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To our knowledge, this is the first report documenting the use of an atomising spray, at ambient, mild processing conditions, to create dissolvable microneedle arrays that can possess novel, laminate layering. Presently available materials seem adequate to meet requirements.

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In an in vivo quest for binding partners of the TIMP-3 protein in the subretina, we identified epidermal growth factor-containing fibulin-like extracellular matrix protein 1 (EFEMP1, also known as fibulin 3) as a strong interacting protein. Extending the classic integral images and the integral histograms, it represents the global information of two correlated images. Autoradiographic localization of protein synthesis in vitro in the ovary of the prepuberal rat The lower cost and the high specificity of ELISA test are appropriate for developing countries, and such systematic screening for sickle cell anaemia is therefore feasible. A total of 594 patients undergoing stenting of 639 saphenous vein grafts were prospectively randomized, using a noninferiority design, to compare 2 treatment strategies: control (distal protection whenever possible) or test (proximal protection when possible, distal when not).

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Reappraisal of the comparative cost of human locomotion using gait-specific allometric analyses. However, mPEPCK siRNA transfection induced changes in neither the mitochondrial membrane potential nor the expression levels of mitochondrial apoptotic factors such as Bax, Bcl-2, and Bad. The PCQ-based WNS system improves specificity for detecting colorectal cancer, particularly when the WNS exceeds 70. The available tools for miRNA target prediction encompass a range of different computational approaches, from the modeling of physical interactions to the incorporation of machine learning. Adenosine deaminase and terminal deoxynucleotidyl transferase in human lymphomas: an aid to the diagnosis and subclassification of lymphoblastic lymphomas.

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The primary mechanism underlying antagonism among microorganisms is the production of antagonistic substances called antibiotics that inhibit the growth of pathogens. Single cases of B- and T-lymphoblastic leukemia/lymphoma occurring after remission of JMML, and JMML occurring after remission of B-lymphoblastic leukemia have been reported in the literature.

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There is no evidence from randomised controlled trials about the management of pain in ALS. Our study in an inbred mouse model and in three ethnically distinct populations indicates complex interactions of NR1H4 alleles and other risk factors for the development of cholelithiasis.

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Ozone is an important disinfecting agent, however its influence on enamel adhesion has not yet been clarified. This pilot randomized trial addressing downstream ACP effects of video versus narrative decision tools demonstrated a trend towards more ACP documentation in video subjects. A comparative DFT study of the mechanical and electronic properties of greigite Fe3S4 and magnetite Fe3O4.

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Extended/advanced monitoring techniques in gastrointestinal endoscopy. Both participants and genetic counselors considered ShaRIT a well-received, comprehensive tool for disseminating individual risk information and clinical care guidelines to Hereditary Breast and Ovarian Cancer Syndrome families.

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Bone for reconstruction must be placed in the correct three dimensional (3D) position in order to achieve a good cosmetic and functional result. Liposomes of phosphatidylcholine prepared in the presence of phosphatidic acid or phosphatidylinositol did not inhibit the lysis of mouse brom RBC by autoantibodies to the same extent as liposomes of only phosphatidylcholine. Phosphorus fluxes were dominated by agricultural production, with agricultural soils accumulating P.

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A J-shaped exposure-risk relationship with a diminishing population exposure over time fitted the observed seasonal pattern in the Danish birth weight data. Biocompatibility and biomineralization assessment of a new root canal sealer and root-end filling material. Morphological examinations of the liver in chronic opisthorchiasis have both diagnostic and prognostic importance. HvLUX1 is a candidate gene underlying the early maturity 10 locus in barley: phylogeny, diversity, and interactions with the circadian clock and photoperiodic pathways.

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All isolates were identified as Leptospira interrogans, serovar Canicola. Seed development includes an early stage of endosperm proliferation and a late stage of embryo growth at the expense of the endosperm in Arabidopsis thaliana. We describe a family illustrating the diagnostic difficulties occurring when pyridoxine-responsive cystathionine beta-synthase (CBS) deficiency presents with thrombotic disease without associated ocular, skeletal, or CNS abnormalities, a situation increasingly recognized.

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Nonsmooth optimization techniques for semisupervised classification. Measures of social function and participation in musculoskeletal populations: Impact on Participation and Autonomy (IPA), Keele Assessment of Participation (KAP), Participation Measure for Post-Acute Care (PM-PAC), Participation Objective, Participation Subjective (POPS), Rating of Perceived Participation (ROPP), and The Participation Scale. In the case of low molecular weight metabolites, an increasing trend was observed for hippuric acid, not for phenolic acids.

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Previous studies have shown that the use of this Doppler can improve detection and salvage rates as it provides an earlier warning than the current method of clinical assessment. This study investigates the correlation of sprout angiogenesis and ECM microenvironment using in vivo and in vitro 3D angiogenesis models. Generally the septum pellucidum is involved in direct extension of tumors that arise from the neighboring structures, principally the corpus callosum. The pain syndrome in the cardiac region in congenital block of cervical vertebrae

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The costoclavicular compression syndrome and the cervical rib syndrome can cause arterial complications of the subclavian artery: mural thrombosis, occlusion and aneurysma. Generation of new neurons is of particular interest because of the potential to treat diseases of the nervous system, such as neurodegenerative disorders and spinal cord injuries, with cell replacement therapy.

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The nature of the phase transition is probed in static SANS measurements and with time-dependent SANS measurements after a temperature jump. Effects of the cryptochrome CryB from Rhodobacter sphaeroides on global gene expression in the dark or blue light or in the presence of singlet oxygen. On the long run, growth velocity shifted upward in a wave-like pattern, stabilizing on a significantly higher level than before the transfer of application. Brief Pain Inventory, American Academy of Orthopaedic Surgeons (AAOS) Lower Limb Core Scale, Short Form (SF)-12, quality-adjusted life years.

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Consequently, dysregulation of death receptor-dependent apoptotic signaling pathways has been implicated in the development of autoimmune diseases, immunodeficiency, and cancer. Relative DNA content in lymphocytes and buccal mucosa of patients with sex chromosomal anomalies. In patients where angiotensin II receptor antagonists and angiotensin-converting enzyme inhibitors are contraindicated or not tolerated, calcium-channel blockers should be the second option. Hence it is important that gynecologists who start seeing women at an earlier age than cardiologists should be aware of cardiovascular disease. Specifically, arterial tissue was investigated during experimental research and parameter estimation studies, due to medical, scientific and socio-economic importance of soft tissue research.

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Experiences with electrical stimulation of limited parts of the brain in the baboon and man. Our findings suggest a relationship between a dysregulated vasopressin system and cardiometabolic risk, which could have implications for risk assessment and novel preventive treatments. The proposed method of determining a cell type-specific null model, which accounts for cell type-specific biases, is shown to be capable of achieving a lower false discovery rate at a given significance threshold than current methods. Despite the relatively small number of subjects involved in this trial, who were exclusively Japanese, our results imply that Vis-NIR spectroscopy of the thumb combined with chemometrics analysis may provide a valuable tool for diagnosing CFS.

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Overlay experiments suggest that the receptor can bind to other trypanosome glycoproteins, which may explain this discrepancy. Synthesis of Single-stranded RNA Probes by In Vitro Transcription.

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Chemical cross-linking data suggested that IcsA exists in a complex in the OM. This cross-sectional multicenter study includes 692 patients who completed the questionnaire at the end of their ambulatory treatment. different sensitivity of frog and rat innervated and denervated muscles to d-tubocurarine), or different ionic pathways during activation (hibernating golden hamster). A note on the reactions of Mycobacterium anabanti to carbohydrates A new top-down method of identifying intact proteins is particularly suited to differentiating highly related protein species created by alternative splicing, proteolytic events, and post-translational modifications.

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91 patients who underwent 95 endoscopic transnasal procedures were included in this study. Market surveys revealed that NUCS are important source of household incomes and substantially contribute to poverty reduction.

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Immunogenicity of Pasteurella multocida and Mannheimia haemolytica outer membrane vesicles. In addition, plasma insulin concentration, liver phosphorylated Akt/Akt and phosphorylated mTOR/mTOR levels were significantly higher in the MCT-fed group than in the LCT-fed group. Although studies investigating the nature of Ab-secreting cells (ASCs) during acute infection with influenza or dengue virus found that the ASC response was dominated by virus-specific IgG secretion, the Ag specificity and phenotype of ASCs during primary acute viral infection were not identified. Branchial cleft anomalies are equally frequent in men and women, and equally distributed on the left and right side of the neck.

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MR-arthrography assessment after repair of chronic meniscal tears. In our study alcoholic patients with and without cirrhosis have a decreased serum zinc. Effect of aging on lung structure in vivo: assessment with densitometric and fractal analysis of high-resolution computed tomography data. Publication of a wide range of studies with different designs, study populations, and results has fueled uncertainty about the best way to use PSAV and confused the issue of its utility in the early detection setting.

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We evaluated the distribution of values for prostatic acid phosphatase (EC 3.1.3.2) activity and zinc concentration in semen of 80 men without clinical evidence of prostatic disease. Allogeneic kidney cells at all doses were surprisingly ineffective in inducing tolerance of either kidney or skin allografts, so the existence of kidney-specific transplantation antigens remains problematical. Novel SOST gene mutation in a sclerosteosis patient from Morocco: a case report.

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Combined effect of electrical stimulation and cisplatin in HeLa cell death. Micellar carriers comprised by PEG-PLA block co-polymers were formulated by the solvent displacement method in which the simultaneous encapsulation of Crizotinib and Sildenafil was promoted. Partial breast feeding is the dominant mode of feeding in our community, although the influencing factors and behavioral factors are similar in breast feeding and partial breast feeding groups. Psychological factors in pelvic/urogenital pain: the influence of site of pain versus sex.