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Losartan is used alone or in combination with other medications to treat high blood pressure. Losartan is also used to decrease the risk of stroke in people who have high blood pressure and a heart condition called left ventricular hypertrophy (enlargement of the walls of the left side of the heart). Losartan may not decrease the risk of stroke in African Americans who have these conditions. This medication is also used to treat kidney disease in people who have type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) and high blood pressure. Losartan is in a class of medications called angiotensin II receptor antagonists. It works by blocking the action of certain natural substances that tighten the blood vessels, allowing the blood to flow more smoothly and the heart to pump more efficiently.

High blood pressure is a common condition, and when not treated it can cause damage to the brain, heart, blood vessels, kidneys, and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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NO synthase-dependent increases in extracellular citrulline levels in the nucleus accumbens in an emotional conditioned reflex. This is a quantum mechanics/molecular mechanics method (QM/MM) that makes use of the mean field approximation (MFA) and that permits one to simultaneously optimize the electronic structure and geometry of the solute molecule and the solvent structure around it.

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Nevertheless, all of the available grafts have specific characteristics and can feature certain complications. There is a transformation in behavior in the visual system of cats and primates, from neurons in the Lateral Geniculate Nucleus (LGN) that are not tuned for orientation to orientation-tuned cells in primary visual cortex (V1). The PRAETORIAN trial is a randomized trial that aims to gain scientific evidence for the use of the subcutaneous ICD compared with the transvenous ICD in a population of patients with conventional ICD with respect to major ICD-related adverse events. Stress hyperglycaemia in patients with first myocardial infarction.

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In contrast, TGF-beta expression is highest at the anterior pole. We suggest that E-cadherin plays an important role in the macroscopic growth as well as microscopic differentiation of early gastric carcinomas. Although straightforward, this approach cannot exploit the full potential offered by the probabilistic modeling, as only the posterior mode is sought.

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The data from this study was compared with a previously published study in this practice, which evaluated the adherence rates for the treatment guidelines before the changes, to determine effectiveness of the modifications. These data were fitted to the Hill equation by a nonlinear regression analysis and the statistically most probable values obtained for the Hill coefficient (n), A0.5, and V were, respectively, 2.08, 0.82mM, and 1030 mumol/g of protein per hour. Laparoscopic nephrectomy and transdiaphragmatic resection of inferior solitary lung tumor: technique and feasibility of the approach. The HIGH(AKL) cluster was more likely to have greater hip anteversion and navicular drop. Absorption of aminoethyl cysteine ketimine decarboxylated dimer in mice: effect on plasma antioxidant potential.

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In Ussing chamber experiments with human tissue, both the metabolite formation and apical efflux of the metabolite were increased for the nanoparticulate solid dispersion compared with a physical mixture, in line with the results in intestinal slices. Gaining the upper hand: comparison of alphabetic and keyboard positions as spatial features of letters producing distinct S-R compatibility effects. Statistical analyses were performed using Cox regression and the Kaplan-Meier method.

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Women who were underweight in adolescence had better functioning in older adulthood than their normal weight counterparts. Changes in limb posture at impact were interpreted as active adaptations that compensate for passive mechanical effects. A mannitol based phase selective supergelator offers a simple, viable and greener method to combat marine oil spills.

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The way they drew on the temples showed an asymmetry that was the mirror reversal of that of right-handers, as found in a previous study. Our findings suggest that elevated BP increases the risk of hematoma enlargement. Maximum likelihood approaches are emerging as robust tools for solving the image classification problems that are posed by such samples. Influence of CYP2D6 polymorphisms on symptomatology and side-effects of patients with schizophrenia in Malaysia.

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No clear benefit has been demonstrated on pharmacy personnel-delivered NRT interventions. Rats were treated with 0, 0.1, 1.0 or 10 mg/kg per day PNU157706 for 28 days. Chimeras predicted to have limited structural disruption, as defined by the SCHEMA algorithm, displayed CO binding spectra characteristic of folded p450s. Effects of alpha-fluoromethylhistidine on sleep-waking parameters in rats.

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Both affections were probably transmitted by a single pleiotropic gene. These findings indicate that CSF flow-mediated neuronal guidance is likely to be dominated by the action of the ependymal cilia in the lateral ventricles, whereas CSF dynamics in the centre regions of the ventricles is driven predominantly by wall motion and choroid plexus pulsation. Spatial structure and interspecific cooperation: theory and an empirical test using the mycorrhizal mutualism.

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This unexpectedly large size of the proinsulin mRNA is discussed. Our results suggest that the deregulation of ACE and ACE2 plays an important role in tourniquet-induced renal injury and that ACE2 up-regulation to restore the proper ACE/ACE2 balance is a potential therapeutic strategy for kidney injury.

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Our results suggest that significant microstructural changes in WM continue throughout adolescence and are associated with corresponding age-related changes in cortical GM regions. The findings provide new information on the regulation and role of this ncRNA in P. Workers employed at the Savannah River Site (SRS) were potentially exposed to a range of chemical and physical hazards, many of which are poorly characterized.

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Nonrigid registration (NRR) of MR images has previously demonstrated sub-voxel registration accuracy although its accuracy and precision in determining strain has not been evaluated. Methotrexate for uveitis associated with juvenile idiopathic arthritis: value and requirement for additional anti-inflammatory medication.

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Soil microcosms were amended with a range of concentrations of TNT for 30 days. Statistical analysis included discriminant analysis, Kruskal-Wallis test, nonsupervised learning algorithm P-index and Beale statistic.

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The study suggests that 4 of the NEO PI-R dimensions are logically categorized along the JobMatchTalent main scales: (1) Order and Thoughtfulness, (2) Energy and Extraversion, (3) Social Adaptation and Interest, and (4) Emotion Control. The study covered an eleven month time period and used system logs as well as questionnaires including a modified questionnaire of user interaction satisfaction QUIS. Two QTH light-curing units (Visilux 2, at 550 mW/cm2, and Optilux 501, at 1,360 mW/cm2) and a LED unit (Elipar FreeLight, at 320 mW/cm2) were used for curing. In Studies 1 and 2, sequences of task choices and the corresponding transition sequences (task repetitions or switches) were analyzed with the help of dependency statistics.

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JOT procurement transplant coordinators (PTC) play roles in obtaining consent from relatives for organ donation, donor evaluation and management, organ recovery management, organ transport, and care of donor families during and after donation. Compared to men with similar OSA severity, women are heavier users of health care resources.

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We compared the microscopic and nuclear morphometric characteristics of classical chromophobe renal cell carcinoma (C-ChRC) and renal oncocytoma (RO) and applied meaningful characteristics to differentiate eosinophilic chromophobe renal cell carcinoma (E-ChRC) from RO that has overlapping histology (RO-OH) with E-ChRC to know the usefulness of nuclear morphometry. Because it is difficult to diagnose before surgery, the morbidity and mortality rates for obturator hernia are high. Although serum albumin is commonly used as a nutritional marker, data is lacking on serum albumin levels in the elderly. Clinical analysis of childhood pancreatoblastoma arising from the tail of the pancreas. The ability to quantitate tissue parameters helps in selecting appropriate imaging sequences and may be of use in following the progress of tumors.

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The results of this study show that age, co-habitation, occupation, smoking, and self-rated stress level were significantly related to the drinking patterns for men, whereas education, co-habitation, smoking, and self-rated stress level were significant factors for the drinking patterns of women. The relationship of pulmonary blood flow and vascular resistance to pulmonary artery pressure was examined in pentobarbital-anesthetized open-chest dogs. High-efficiency transfection and siRNA-mediated gene knockdown in human pluripotent stem cells.

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Regarding their hope for an ordinary life, patients could benefit from the relief of adverse effects and information, for instance, on how to resume sexual activity. They were randomly divided into group A (combined anteroposterior surgery) and group B (posterior-only surgery). Maximum hip torque is larger with arms but maximum knee torque is larger without arms. Addition of Spiramycin during incubation was of little influence on the growth and the composition of the flora.

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Meanwhile, experiences with adult cases have introduced new drug treatment options for children, especially those with chronic disease and significant bleeding. The clinic and laboratory in the early diagnosis of cancer of the lung cerevisiae has an alternative fusion mechanism that requires ER SNAREs. This study aimed to clarify the validity of hepatectomy for treating HCC in RD patients, and to compare postoperative courses in RD and non-RD patients. The vitamin D receptor (VDR) is a member of the nuclear receptor superfamily and plays a central role in the biological actions of vitamin D.

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Clearance of hepatitis C viremia associated with cellular immunity in the absence of seroconversion in the hepatitis C incidence and transmission in prisons study cohort. A similar pattern of grains is seen following absorption of either linoleic acid or safflower oil. We hypothesize that susceptibility weighted imaging (SWI) is sensitive enough to detect intratumoral microvessles and microbleeding in renal cell carcinoma, which can be used to grade CRCC.

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Four Fisch type IIIa tumors were removed completely from only an ENE approach. The tight junction forms a barrier that limits paracellular movement of water, ions, and macromolecules. Development of a radio frequency ion source with multi-helicon plasma injectors for neutral beam injection system of Versatile Experiment Spherical Torus.

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Emerging data suggest that the remarkable clinical efficacy of these agents may be related to their ability to target the breast cancer stem cell (CSC) population. Memantine and MTEP both reduced attack bite frequency in the instigation condition without reducing locomotor behavior.

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We describe an experiment in which ocular refractive state was objectively and subjectively measured while viewing two kind of stimulus: letters on a bright background and a punctual source of light in a dark background. NgR is expressed in both the cell body and the prominence of OLPs. Muscarinic and purinergic receptor expression in the urothelium of rats with detrusor overactivity induced by bladder outlet obstruction. Some studies suggest that humans adapt to feedback delays with lasting changes in motor behavior (aftereffects) and a recalibration of time perception. Depressive symptoms were measured using the Patient Health Questionnaire-8.

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All patients showed reduced coronary flow during exercise, an evidence of early signs of coronary insufficiency. RT-PCR and immunohistochemistry were carried out in twenty women with normal menstrual cycle to confirm the expression of AQP1 in endometrium and locate it. Selected anti-clonogenic compounds might be further investigated as potential adjuvants targeting melanoma stem-like cells in the combined anti-melanoma therapy, whereas selected cytotoxic but not anti-clonogenic compounds, which increased the frequency of ABCB5-positive cells and remained slow-cycling cells unaffected, might be considered as a tool to enrich cultures with cells exhibiting melanoma stem cell characteristics. There are high numbers of travellers, Manush, Gypsy and Roma people in France, with secular traditions, an orally-transmitted culture and a community-based way of living.

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To try to learn more about down-stream effects on MEN1 gene inactivation, we used the BON1 cells, showing low levels of endogenous menin, and transfected them with a MEN1 gene construct. There was no definitive correlation between EBV reactivity and NHL.

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The objective of this study was to assess whether treatment with sustained-release bupropion (Wellbutrin-SR) produces alterations in electroencephalographic (EEG) sleep that are associated with clinical response to the drug. The goal of being planned and prepared for pregnancies is still only an abstract concept. Diabetes surgery in nonobese or moderately obese patients is an emerging topic. Ectopic expression of miR-214 suppressed proliferation, migration, and invasion in vitro, tumor growth and liver metastasis in an in vivo xenograft mouse model, whereas miR-214 knockdown promoted proliferation, migration, and invasion in CRC cell lines. The protein levels of PMA or macrophage-colony stimulating factor (M-CSF)-stimulated type 1 macrophage scavenger receptor (SRA) were analyzed.

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Hemorrhagic complications after radiofrequency ablation can usually be treated conservatively, but such complications can be massive and fatal in some cases. Knockdown of DSG3 significantly increased the interaction of plakoglobin with the transcriptional factor TCF and suppressed the TCF/LEF transcriptional activity.

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Skin lesion may be primitive or secondary to another pre-existing tuberculosis lesions, it may be have many clinical appearance with the same characteristics, as knew as, long evolution and anesthetics sequels. Cell lines of diverse origin and which are permissive in the in vitro cell fusion assay have been identified and the pattern of relative susceptibilities is the same for both HENV and NIPV, implying that both viruses use the same cell receptor. We found that under photopic conditions the optimum refractive state of the accommodating eye is significantly more myopic when maximizing perceived quality of a point source on a dark background compared to a conventional letter chart with black letters on a white background. Evaluation of mass-like consolidation after stereotactic body radiation therapy for lung tumors.

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Influence of human leucocyte antigen disparity and graft lymphocytes on allogeneic engraftment and survival after umbilical cord blood transplant in adults. In the following chapter, we describe fluorescence-based methods for studying the interaction of mRNA with the bacterial initiation complex. Children who participated in WIC had an increased probability of having a dental visit, were more likely to use preventive and restorative services, and were less likely to use emergency services.

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This paper describes further exploration of the effect of polysorbate 80 on the absorption, distribution, and elimination of methotrexate (MTX). Recent experiments have shown that the rare earth compound LiHo(0.045)Y(0.955)F(4) freezes, but that the transition is unreachable because of dynamics that are 10(7) times slower than in ordinary spin-glass materials. Acute aortic insufficiency was found in 24 patients, and hemiplegia or hemiparesis in 4.

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Nowadays, some intrapartum injuries to the pelvic floor can be successfully detected with ultrasound in the immediate postpartum period. RTs were slower on trials that required attention to the go signal and in both attention conditions and at both SOAs shortened in the presence of a blink-eliciting stimulus. Ovarian cancer cells with CtBP2 knockdown did not display increased sensitivity to the PARP inhibitor Olaparib. Abnormal neurodevelopment was evident in one third of children with both T-CHI and P-CHI, early presentation and severe CHI being risk factors. Identification of a novel RPGR exon ORF15 mutation in a family with X-linked retinitis pigmentosa.

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To evaluate a pilot program of providing child restraint system (CRS) checks by certified technicians with well-child care in an urban health center serving a low-income community. The clusters exist owing to the conformation flexibility of the protein molecules, leading to exposure of hydrophobic surfaces and enhanced intermolecular binding. Taken together, our results show the congruence of in vivo and in vitro data on nucleotide excision repair in humans. We also studied the levels and mechanisms of resistance present in 34 Brachiaria hybrids developed by CIAT.

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This included one-to-one training of key nurses of the nasojejunal tube placement technique and a supervised nasojejunal placement with either the senior nurse or dietitian. To address the biochemical function of LBD proteins, we identified a 6-bp consensus motif recognized by a wide cross-section of LBD proteins, and showed that LATERAL ORGAN BOUNDARIES (LOB), the founding member of the family, is a transcriptional activator in yeast. We describe our initial experience with the use of the TriVascular Ovation endograft system for the treatment of abdominal aortic aneurysms (AAA).

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This paper presents the results of an expert review process used to transform the identified information needs into a concise set of research questions that can be pursued through new scientific inquiry in PHSSR. As stem cells have a potential for future application in transplantation and regenerative medicine, this article also reviews the literature on major histocompatibility complex expression on stem cells of the reproductive tract, because of its immunogenic effects, but also because of its potential expression of HLA-G, a potent immunomodulator mainly associated with trophoblast cells. Peer support and interpersonal psychotherapy groups experienced decreased prenatal depression, anxiety and cortisol. In addition, in patients with central adiposity and the MetS, enhanced intravascular ET-1 activity coexists with decreased nitric oxide (NO)-dependent vasodilator capacity, suggesting a prevalence of vasoconstrictor mediators in vessels of obese individuals.

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The attachments of the anteromedial and posterolateral fibre bundles of the anterior cruciate ligament: Part 1: tibial attachment. Interference between mobile phones and pacemakers: a look inside. A computational model of in vitro angiogenesis based on extracellular matrix fibre orientation. The third case was treated and completely healed with vacuum-assisted closure therapy alone.

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Dual action of antidepressant drugs (MAO inhibitors) on insulin release. Effective treatment agents include follicular maturing drugs and gonadotropin releasing hormone antagonists in the follicular phase, human chorionic gonadotropins and leuprolide acetate at time of peak follicular maturation and progesterone in the luteal phase.

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Virus inactivation on hard surfaces or in suspension by chemical disinfectants: systematic review and meta-analysis of norovirus surrogates. Measurements are made before scientific name of sumatran elephant in forest and after a period of cycling exercise. The goal of this study was to identify differentially methylated genes in HPV positive versus HPV negative primary HNSCC genomes with clues to signaling networks. Recent studies suggest that, while reward anticipation and reward prediction errors are encoded in the midbrain and the ventral striatum, reward receipts are encoded in the medial orbitofrontal cortex.

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Quadratic electro-optic properties of Pb(Mg1/3Nb2/3)O3-PbTiO3 transparent ceramics under both DC and AC bias. Medical Malpractice: duty of care may arise from informal contact. Proliferation of epithelial cells on PDMS substrates with micropillars sulfasalazine drug action of acyclovir fabricated with different curvature characteristics. We report the development of the Staphylococcus aureus Microarray meta-database (SAMMD) which includes data from all the published transcriptional profiles.

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Programmed cell death 1 (PD-1) is an inhibitory immune receptor that regulates T cell piroxicam gel 112gdx function, yet the molecular events that control its expression are largely unknown. The purpose of the present study was to present a method for assessing the chronological age based on the relationship between age and morphological parameters of maxillary central incisors.

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Argon isotopic composition of Archaean atmosphere probes early Earth geodynamics. We attempted to find a better way for diagnosis of female BOO by performing VUDS. Lipid composition of the human eye: are red blood cells a good mirror of retinal and optic nerve fatty acids? saprophyticus retrieved (KEGG) from web server were found to be non homologous to the host Bos taurus, out of which 39 pathways were found to be in cytoplasm, 2 in cell wall and 3 in the cell membrane. Moreover, the PSA progression-free survival at fosinopril 10 mg bijsluiter zaldiar 3 months was validated only for cytotoxic drugs, and the various measures of progression/delay have not been confirmed by large studies.

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Phosphorylation of MeCP2 at S229 or S80 influenced selective in vivo interactions with the chromatin factors suhagra dosage HP1 and SMC3 and the cofactors Sin3A and YB-1. PLS is used to reduce the dimensionality of spectrum data and relate them to the concentration.

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Sustained rhythmic firing could be evoked by continuous synaptic drive or long pulses of injected current. The few existing studies of sexual dysfunction in women on hemodialysis are limited by small sample size. After a revision of braxan tabletas de 200 mg available literature including the recent paper of Hurdman et al. Classification of recommendations and level of evidence are expressed in the American College of Cardiology Foundation/American Heart Association format.

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Sexual motivation in males decreased after sodium glutamate, physiological saline producing a tendency to decreased sexual motivation. Clinical utility of the Tower of London--Drexel University, Second Edition (TOLDX) after adolescent traumatic brain injury. Neuronal tracing of oral nerves in a velvet worm-Implications for the indolan 100 mg morphine pills evolution of the ecdysozoan brain. The inverse relation of miR-99a and its target(s) was examined in clinical specimens using real-time PCR and Western blot analysis.

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This study indicates that AIF-1 enhances VSMC growth by autocrine production of G-CSF, and AIF-1 expression may influence VSMC-inflammatory cell communication. Supramolecular materials, dynamic materials by nature, are defined as materials whose components ibuleve maximum strength gelding are bridged via reversible connections and undergo spontaneous and continuous assembly/disassembly processes under specific conditions.