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The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor Primary conjunctival herpetic geographic ulcer in an immunocompetent patient. NLRC5: a NOD-like receptor protein with many faces in immune regulation.

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To investigate the relationship between collagen content and organization with muscle mechanical properties, we studied mdx mice, a model for Duchenne muscular dystrophy (DMD) that undergoes skeletal muscle fibrosis, and age-matched control mice. Left prefrontal cortex activation during sentence comprehension covaries with grammatical knowledge in children. Kidney transplantation in patients with end stage congenital renal disease. Causes of mistaken diagnosis of secretory otitis media in children

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In 2005, the International Committee of Medical Journal Editors established clinical trial registration as a requirement for articles submitted to member journals, with the goal of improving the transparency of clinical research. Iron deficiency screening in the first three years of life: a three-decade-long retrospective case study.

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At 5 min after reoxygenation, piglets were given either saline or N-acetylcysteine (20 or 100 mg/kg/h) in a blinded, randomized fashion. Protein monomers are separated from soluble and insoluble aggregates using size exclusion chromatography, under nondenaturing conditions, and the individual components in the mixture are identified by mass spectrometry and quantitated relative to an unstressed control. CpHMD simulations with a hybrid-solvent scheme and the pH-based replica-exchange (REX) protocol are applied to obtain the equilibrium constants and atomic details of the ionization-coupled conformational exchange between open and closed states of an engineered mutant of staphylococcal nuclease.

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Crystal-induced tissue damage is affected by degradative proteases, cytokines, chemokines, and prostanoids produced by cells stimulated by crystals. For vancomycin, it was 13 million dollars per QALY gained and 95 million dollars per case prevented. This study shows that avian influenza virus H5N1 recombinant proteins produced in mammalian cell system were able to induce neutralizing antibody response.

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Distribution pattern of the Ki67 labelling index in breast cancer and its implications for choosing cut-off values. Review article: The rationale for antidepressant therapy in functional gastrointestinal disorders. Inhibition of NF-kappaB constitutive activation in MMe cells by Bortezomib resulted in in vitro cytotoxicity along with apoptosis and in vivo tumor regression. Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility.

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The impact of huts on physiological stress: a refinement in post-transport housing of male guineapigs (Cavia porcellus). In this article, we introduce, for the first time, evidence of deposits of GS in all layers of the cornea, predominantly in the corneal stroma and in the endothelium. Notch receptors are involved in directing the choice between alternative cell fates in developmental scenarios such as thymopoiesis. A cross-cultural comparison of the developmental evolution of expertise in diabetes self-management.

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This is the first case of radiation-induced carcinoma arising in a cecal neovagina. Numerical simulations of plane wave and Gaussian beam scattering from the hyperlens confirm the semiclassical description. We present here CanGEM (Cancer GEnome Mine), which is a public, web-based database for storing quantitative microarray data and relevant metadata about the measurements and samples.

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Effect of metakaolin on strength and efflorescence quantity of cement-based composites. The orally administered mangiferin (10-100 mg/kg) was well tolerated and did not impair the ambulation or the motor coordination of mice in respective open-field and rota-rod tests, indicating that the observed antinociception was unrelated to sedation or motor abnormality.

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Changes in peripheral thyroid hormones caused by prolonged treatment with amiodarone Radiotherapy effects on anti-tumor immunity: implications for cancer treatment.

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This paper covers the topic of infection in mechanical circulatory support. The diffracted waves are plotted numerically for different parameters of the incident field.

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Molecular comparisons of the Culex pipiens (L.) complex esterase gene amplicons. Action potentials and insulin secretion: new insights into the role of Kv channels. Daily drug use and daily falls were recorded in 248 nursing home residents with dementia from 1 January 2006 until 1 January 2008. Rotator cuff repair using a decellularized tendon slices graft: an in vivo study in a rabbit model. The method was demonstrated using localized averaged echo time point resolved spectroscopy proton spectroscopy of human brains.

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An algorithm for the accurate calculation of luminescence lifetimes in near-real-time is described. Moreover, we found that, in the presence of a methylated target, GcrA recruits the RNA polymerase to the promoter, consistent with its role in transcriptional activation.

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Expression of Toll-like receptors in enterocromaffin-like cells and their function in histamine release. The idea of wellbeing in the workplace has multiple meanings across organizations and countries in Europe and no comprehensive surveys examining its exact prevalence and overall impact are currently available. Group I patients had decreased coronary sinus flow (4 of 5 patients) or decreased regional flow (5 of 5) during spontaneous angina. Gadoxetic acid-enhanced T1-weighted MR cholangiography in primary sclerosing cholangitis.

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A complex airway network is revealed, wherein the branched maxilloturbinate and ethmoturbinate scrolls appear structurally distinct. PBECs from patients with COPD show significantly higher TNF-alpha-induced release of the neutrophil chemoattractant CXC-chemokines IL-8 and GRO-alpha compared to smokers without airflow limitation. RNA editing especially has increased greatly during mammalian evolution and modulates diverse cellular functions presumably in a context-dependent manner.

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Insertion of an intein gene into the active site of the RB69 DNA polymerase gene renders polymerase activity and phage viability dependent on protein splicing. In CT examinations of intraspinal tumours, intrathecal contrast medium increased the amount of information obtained especially in the thoracic and cervical regions, but was not necessary if myelograms were available. To assess bone mass using total and regional bone densitometry in a group of patients on PD and to determine if serum markers of bone turnover identify patients with low bone mass. On a sanitary-chemical study of two lacquer-paint coatings manufactured from vinyl chloride derivatives

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Injuries of femoral vessels during Toianov-Trendelenburg procedures This new finding indicates that exposure duration may be a more important factor in the induction of asthma than previously understood, and suggests that SHS could be a more fundamental and widespread cause of childhood asthma than some previous meta-analyses have indicated. A dog as well as a human is a host for many species of Bbsl, because borreliacidal ability of serum of dogs and humans is evident only in certain genospecies of Bbsl.

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MSN450 showed the slowest release rate of ibuprofen, followed by MSN300 and MSN100. A comparison of the results obtained from the two strategies reveals that Strategy 2 performs much better than Strategy 1 in determining the reservoir real-time releases throughout the system during flood emergencies in order to minimize flooding, while maintaining all reservoirs in the system in balance if possible. Time interval after radiotherapy and dental implant failure: systematic review of observational studies and meta-analysis. In the cortex the expression of Homer 1a and ania-3 was down-regulated by chronic clozapine and aripiprazole.

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Staphylococcal clumping factor as well as protein A both isolated from strain E 2371 were capable of activate complement, while the fibronectin-binding protein showed no activity. Mitochondria are vital organelles of the aerobic eukaryotic cell. Neck auscultation: a simple new method for confirming tracheal intubation. A logistic multiple regression analysis revealed that a switch of p-Akt control from a PTEN/EGFR- to Her2-after bicalutamide treatment was possible. A retrospective medical record review was conducted for patients with PHHI managed during the last 15 years.

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p53 plays a critical role in a variety of growth inhibitory responses, including cell cycle arrest, differentiation, and apoptosis, and contributes to tumor suppression. Stable reaction products were distinguished from transient species by plotting their extracted mass profiles. Aortocoronary artery bypass: present indications and risk factors. According to its excellent specificity in the diagnosis of fetal asphyxia, the lactate microanalysis is a useful complementary method for the fetal heart rate monitoring, the sensibility of which is well-known.

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FGF17 expression is increased 2-fold in BPH and may contribute to the increased epithelial proliferation seen in this disease. Significant peak shifts of generalization gradients were observed in the direction predicted by adaptation level theory. One hundred and eight Sprague-Dawley (SD) rats were randomly divided into 3 groups: control group, streptozotocin (STZ) group and puerarin group.

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Plasma glucagon concentrations were measured in nine patients before and after renal transplantation. Mesenteric duplex and a computerized tomography mesenteric angiography demonstrate dynamic compression of the coeliac axis during expiration. From the comparison it resulted that the values of gamma(L) determined by the Szyszkowski equation are correlated with those measured only in a limited propanol concentration range because of changes of the constant related to the specific capillary activity in this equation as a function of propanol concentration, particularly in the range of its high concentration. These results suggest that TH plays a pivotal role in the development of the Purkinje cell dendrites.

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The clinical data of 14 cases of patients with pituitary adenoma complicated with dilated cardiomyopathy, treated with resection of pituitary tumor, in PLA General Hospital, from 2005 to 2011, were collected and analyzed. Thus, the aim of this study was to study the occurrence of genetic variants in the GIP and GLP-1 encoding regions of the proGIP and proglucagon genes in type 2 diabetic patients and matched control subjects. We aimed to quantify liver vitamin A after the administration of vitamin A doses to piglets. Human experiments involved the participation of 10 healthy male athletes completing a 180 km road cycling test. On the basis of these data we conclude that (a) the different levels of thyroglobulin synthesis in the two untransformed cell lines are due to stable post-transcriptional alterations in the biosynthesis of thyroglobulin and (b) the transformation of thyroid cells results in a substantial reduction in thyroglobulin gene expression.

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Moreover, changing the source of nitrogen greatly affected the morphology of the yeast-like cells. The volunteers were subjected to evaluation of diuretic activity by maintaining the daily total input-output charts during the course of the study. Movement disorders and atrophy occur in the diaphragm, the most important muscle of respiration, because of mechanical ventilation (MV).

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Following an initial hype on potential NMDA receptor therapeutics, the authors currently see a period of skepticism that, in reverse, appears to neglect the therapeutic potential of this receptor class. Children in the dyslexia group showed increased contrast thresholds compared with the control group in all three conditions, and thus strong evidence for a magnocellular deficit. We confirm the particularly poor outcome of cardiac amyloidosis in the short term.

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It comprises a broad spectrum of disorders and requires multidisciplinary assessment including pediatrics, endocrinology and diabetology, metabolic medicine and genetics. The sequences were also very similar to those from the corresponding genes from most of the human group C rotavirus isolates from other countries. Topical insulin for healing of diabetic epithelial defects?: A retrospective review of corneal debridement during vitreoretinal surgery in Malaysian patients.

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Maximum pain levels (VAS ratings) and jaw range of motion in millimeters (maximum mouth opening, protrusion, right and left laterotrusion) were assessed at baseline, at the end of treatment, and at a three-month follow-up. A 77-year-old female with terminal squamous cell carcinoma of the cheek previously treated with radiotherapy. Here, ozone-adsorption-induced band bending is observed on Ti- and Fe-oxide model surfaces under dry and humid conditions. Over-expression of matrix metalloproteinase-9 (MMP-9) is implicated in the invasion and metastasis of HNSCC. Lifetime exposure to traumatic events among adolescents in contact with the Nigerian juvenile justice systems compared with a comparison group of secondary school students.

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Pentylenetetrazol (PTZ)-induced kindling in rodents is considered a model of human absence epilepsy and myoclonic, generalized tonic-clonic seizure. coli) derived rhBMP-2 displays comparable efficacy to CHO cell-derived rhBMP-2 in vitro and in small-animal models. Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters. Regardless of the availability and ease of administration of either human milk or formula, it is unlikely that any form of external nutriture can equal the advantages provided by intrauterine growth.

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A peculiar form of diaphragmatic hernia: pericardio-diaphragmatic hernia Involvement of surface-bound radicals in the oxidation of toluene using supported Au-Pd nanoparticles. Portal hypertension - Role of transjugular liver biopsy and TIPS. Mortality rates were standardised to the concurrent non-Indigenous population and categorised by age and sex.

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We used standard methodological procedures expected by The Cochrane Collaboration. Quantification of piscine reovirus (PRV) at different stages of Atlantic salmon Salmo salar production. Radiographs were evaluated for AO classification, loss of reduction, length of volar cortex available for fixation, and adequacy of stabilization of the lunate facet fragment with a volar plate.

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The file drawer effect, grey literature, selective publication of results along with commercial interests or lack thereof also influence the selection of publications. Rethinking glycolysis: on the biochemical logic of metabolic pathways.

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Our results imply that temporal dynamics of single cell types is important to understanding hybrid misexpression and its relationship to cis-trans interactions. Individuals with more darkly pigmented skin have greater difficulty producing vitamin D because melanin acts as an effective natural sunscreen, requiring longer sun exposure to produce an adequate daily allotment of vitamin D. This type of changes has not yet been registered in the Catalogue of Somatic Mutations in Cancer database.