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To examine the combined effect of alcohol and folate intake during adolescence on the risk of proliferative benign breast disease (BBD). Secondary isotope effects and structure-reactivity correlations in the dopamine beta-monooxygenase reaction: evidence for a chemical mechanism. Although classification algorithms are promising tools to support clinical diagnosis and treatment of disease, the usual implicit assumption underlying these algorithms, that all patients are homogeneous with respect to characteristics of interest, is unsatisfactory.

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Pneumatic retinopexy by evaporation of fluorocarbon liquids: in vitro and in vivo results. In persistent central serous chorioretinopathy (CSC) resolution of detachment can be achieved by photodynamic therapy. In vitro protein degradation of 38 sainfoin accessions and its relationship to tannin content by different assays. The views and practices of current trainees can provide important insight into the proactive role social media can play in the delivery of more effective health care during an era in which social media usage is invariably increasing for medical professionals and patients.

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(ii) The majority of patients undergoing single or multivessel PCI can be discharged within 10 h postprocedure. Determining tetrabutylol and tetraethylol in the air of industrial premises and in waste water (condensate) There are two strategies to deliver active compounds: conventional drug delivery systems based on transport and release of active compounds in biological compartments and nanoreactors that transport active compounds and permit them to act in situ, behaving like rudimentary artificial organelles. Angiotensin II AT1 receptor blockade by telmisartan reduces impairment of spatial maze performance induced by both acute and chronic stress. Further study revealed that knocking-down of Sry expression resulted in feminization of gonad development in mouse embryos and the expression level of Sox9 and Wt1 gene was also significantly changed by downregulation of Sry.

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Autologous transfusion appears to be a safe procedure for patients with severe coronary artery disease. Bilateral middle cerebral artery aneurysms: a comparative study of unilateral and bilateral approaches. Detection of health complaints from the occupational psychologic viewpoint--experiences with the use of the Complaint Questionnaire in female workers Every year patients are brought to our hospital who have nearly drowned in the local river after a jump from a bridge (approximate height 16-22 meters).

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Design and operating experiences of full-scale municipal membrane bioreactors in Japan. A quantitative assay for the stimulus-response relationship in bacterial chemotaxis has been developed by measurement of tumble frequency.

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We report a 12-year-old boy with history of swelling appearing on the right side of the neck only on straining, coughing, or during a Valsalva maneuver. After 40 pairings CRs were observed in 87,5 per cent of trials for cardiac and in 78,5 per cent cases for respiratory components. For comparison, a group of animals was held in semicaptivity close to Tunis.

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In contrast, the excitability of the short latency pathway from masticatory cortex to digastric motoneurons, and the excitability of the digastric reflex evoked by electrical stimulation of the mucosa of the tongue were not significantly affected by quipazine administration. Penalized-likelihood image reconstruction for digital holography. The beta2 soluble guanylyl cyclase subunit in mammals and similar ones in Manduca and Drosophila are active in the absence of additional subunits and there is evidence that Drosophila and Anopheles also express an additional subunit that enhances this activity.

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They are not in active cell cycle and do not express Ia-like (HLA-DR) antigens but appear to be capable of self-renewal in vitro. We argue that one major pathway by which OT exerts its positive effects on affiliative and social behaviors is the attenuation of automatic neural responses, which in turn leads to increased approach behaviors and decreased social avoidance.

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Double coronary artery anomaly in an elderly asymptomatic patient with positive electrocardiogram stress test. In 56 healthy volunteers short, middle and long latency somatosensory evoked potentials were recorded bilaterally. Reduced cardiac 123I-MIBG uptake reflects cardiac sympathetic dysfunction in Lewy body disease. Using risk-set sampling, we matched 10 controls to each case based on hospital admission, calendar time (within 6 wk), cohort entrance (within 6 wk) and age (within 5 yr).

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Only randomised controlled trials of women undergoing either total or subtotal hysterectomy for benign gynaecological conditions were included. Treatment of mammospheres with salinomycin reduced the expression of SOX2 indicating a selective targeting of cancer stem cells. Surgery was performed and anatomopathological examination confirmed the diagnosis of compact osteoma. Outcome of hemato-oncologic patients with and without stem cell transplantation in a medical ICU. This paper presents the implementation of a framework for computer-assisted neurorehabilitation that intends to address the need for more personalized healthcare technologies.

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Increase in radioresistance of corneal epithelial cells during regeneration In fact, the analysis of genotypic disequilibrium between loci detected signals of population substructure when all the individuals of Alpine populations are pooled in a single group. We also observe that the histone modification mark, histone H3 lysine 36 tri-methylation (H3K36Me3), exhibits different patterns around the cleavage sites of genes using multiple polyadenylation sites from those of genes using a single polyadenylation site.

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Disagreements were resolved by discussion, and a third review author was involved in the case of no consensus. Seventy-one one-year follow-up questionnaires (twenty-five Sports/Knee, twenty-five Foot and Ankle, sixteen Hip and Knee, and five Lower Limb Core instruments) were returned.

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We find that the adaptive and bounded investment returns can significantly promote cooperation. In the LAVA group the end-to-end anastomosis was executed on CCA by means of application of the three interrupted sutures and subsequent laser soldering of the ICG-infused patch. We establish that the major mRNA decay pathway regulates FLO11 expression.

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According to the distribution of free air, we divided the peritoneal cavity into supramesocolic compartment and inframesocolic compartment. Morphological integration in the hominin dentition: evolutionary, developmental, and functional factors.

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The virus genome replication was decreased in MCM2 knockdown cells. Genetic contributions to phenotypic variation in general intelligence have been studied extensively. The case for a member of the RNAi RNA-directed RNA polymerase family residing in 0305phi8-36 was strengthened by extending the hidden Markov model of this family.

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For inputs generated by a non-Poisson process with positive autocorrelations, both synapses can transmit more information per vesicle release than a synapse with perfect transmission, although the information increases are greater for the depressing synapse than for a constant-probability synapse with the same average transmission probability. Animal experimental studies on wound healing following administratio of adhesive (methyl-2-cyanoacrylate monomer) In this context, we describe a patient-reported questionnaire (the Patient-Tracked Symptoms questionnaire) that contains questions on the presence of signs/symptoms of PTS. All nonuremic patients with PHPT during the period 1995-2008 were identified using the Kaiser Permanente-Southern California laboratory database, encompassing 3.5 million individuals annually.

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Here, we demonstrate the applicability of the loop-mediated DNA amplification method (LAMP), an isothermal DNA amplification technique, to be used in pollen analysis. Acetylation rates and monthly liver function tests during one year of isoniazid preventive therapy. The stem kernel is a natural extension of the string kernel, specifically the all-subsequences kernel, and is tailored to measure the similarity of two RNA sequences from the viewpoint of secondary structures. Practical approach to implementing dietary therapy in adults with eosinophilic esophagitis: the Chicago experience. Multipollutant indicators of mobile source impacts are developed from readily available CO, NOx, and elemental carbon (EC) data for use in air quality and epidemiologic analysis.

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The late luteal phase in infertile women: comparison of simultaneous endometrial biopsy and progesterone levels. The IMGs felt that induction needed to be an on-going, iterative process of learning which continued throughout training, with a more effective individualised learning needs analysis at the start of GP training. Serological evidence is presented that two chemically-induced (by methylcholanthrene and 3,4-benz(a)pyrene) sarcomas of C3HF mice contain cross-reacting tumor-associated cell-surface antigens. Outcome expectancies, descriptive norms, and alcohol use: American Indian and white adolescents. Twenty-one men and women aged 55-64 years with lower education levels were interviewed about using a decision aid to make their screening decision.

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We validate the algorithm by applying it to networks whose community structures are known. XAGE-1a and XAGE-1d are potential biomarkers of lung squamous cell carcinoma.

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Tungiasis is a parasitic skin disease due to the permanent penetration of the female sand flea T. To what extent this additional information will help us in making better therapeutic decisions needs to be studied in clinical trials. Phytopharmaceuticals having a base of such origin offer high advantages as they come with safety profiles, and often allow extrapolation of the HOSU data, under certain circumstances. During the HF feeding WT mice gained significantly more weight than chow-fed animals, while c-Ski mice were partially resistant to the effects of the HF diet on weight. A national study of eHealth standardization in Finland--goals and recommendations.

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The impact of chronically diseased coronary arteries and stenting on the corrected TIMI frame count in elective coronary angiography and percutaneous coronary intervention procedures. Absence of heart-rate effects in isolated frog heart irradiated with pulse modulated microwave energy.

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The proposed method does not require any chromatographic separations, but only needs a small volume of an aqueous salt solution for releasing captured molecules. Comparison of a chlorambucil-prednisolone combination with an azathioprine-prednisolone combination for treatment of chronic enteropathy with concurrent protein-losing enteropathy in dogs: 27 cases (2007-2010). Oxidation of the modified polysaccharide with periodate did not destroy the 2-amino-2-deoxygalactose residues, thus indicating that they were substituted at position 3. Lower serum hepcidin and greater parenchymal iron in nonalcoholic fatty liver disease patients with C282Y HFE mutations. However, the propensity for some tumors to spread through lymphatics suggests that lymphangiogenesis plays a similarly important role.

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The methodological design and statistical methods of most studies evaluating reliability and criterion validity were sufficient, and found the outcome measures to be reliable and valid. Demographic stochasticity is important in determining extinction risks of small populations, but it is largely unknown how its effect depends on the life histories of species. Before we do anything, our brain must first construct a neural correlate of the various mental operations needed. OPN deficiency enhanced the susceptibility to DEN, which was more apparent in females than males. Changing the social opinions of intellectual disability can help to avoid stigmatizing these people with intellectual disability.

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The patient selection criteria were as follows: skeletal and dental Class II malocclusion due to retrognatic mandible, normal or low-angle growth pattern, post-peak growth period, no extracted or congenitally missing permanent teeth, and minimum crowding in the lower dental arch. Effects of intensive antiplatelet therapy for patients with high on-treatment platelet reactivity after coronary stent implantation Here, we determine VM capacity and expression of stemness genes (Oct4, Sox2, Nanog and CD133) in well- and poorly-differentiated HCC cell lines.

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Wnt-promoted Isl1 expression through a novel TCF/LEF1 binding site and H3K9 acetylation in early stages of cardiomyocyte differentiation of P19CL6 cells. The adjusted mortality rates for potentially exposed workers were slightly greater than those for nonexposed workers for most causes examined.

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The markedly different mode of mesoderm formation in anuran and urodelan amphibians (which is related to the early double-layered nature of the anuran blastula wall in contrast to its single-layered nature in the urodeles), but particularly the fundamentally different place and mode of origin of the primordial germ cells in the two groups of amphibians, strongly pleads in favour of a very ancient bifurcation in the phylogenetic history of the two groups, even suggesting a polyphyletic origin from different ancestral fishes. Dysinhibition of the PVN with bilateral microinjection of bicuculline (1 mm, 500 nl) in normal sheep increased MAP, HR and CSNA, but decreased RSNA, whereas in HF bicuculline had no effects on MAP, HR or CSNA, but inhibited RSNA. Identifying new predisposing T1D markers or combinations of markers in a large, well-characterised case-control collection may be important for future T1D prevention.

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Highly enantioselective synthesis of chiral allenes by sequential creation of stereogenic center and chirality transfer in a single pot operation. The World Health Organization International Classification of Functioning, Disability, and Health: a model to guide clinical thinking, practice and research in the field of cerebral palsy.

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In men, hypoandrogenism is associated with features of the metabolic syndrome, but the role of sex hormones in the pathogenesis of the metabolic syndrome and diabetes is not well understood. Dose related effects of androstenedione were not observed on the development of soft tissues. Moreover, the mean blood loss and intraoperative complication rate in the robotic group were significantly lower than those in the laparoscopic group.

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The clinical signs of pregnancy toxaemia at first examination were less severe than those described in ewes in other countries. This 40-patient evaluation of superabsorbent dressing DryMax Extra (Aspen Medical) was conducted within a large UK primary care organization adhering to an agreed evaluation protocol as approved by clinical governance. In the SAH group, there was a slight postoperative decline only in verbal memory after left-sided resection, but other memory function was well preserved.

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The air monitoring data were measured for CO, SO(2), NO(2), and PM(10) concentrations at 27 monitoring stations in Seoul. Cardiac output and coronary, mesenteric, and renal bloodflow were measured with implanted flow probes.

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These mutant mice displayed impaired glucose tolerance and significantly reduced insulin secretion. The paper presents a non-invasive method and system for a long-term and continuous monitoring of the central aortic pressure (CAP) waveform and the augmentation index (AI).

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To investigate the relationship between functional tooth units (FTUs) and nutritional status. Distributions of immunoglobulin-containing cells in alimentary tract, spleen, and mesenteric lymph node of the pig demonstrated by peroxidase-conjugated antiserums to porcine immunoglobulins G, A, and M. The radiological appearances of 22 histologically proven epidermoid and dermoid tumours occurring in four sites are presented - (1) the petrous apex and cerebellopontine angle, (2) the suprasellar region, (3) the cerebral hemispheres and (4) the cerebellum and 4th ventricle. Multifunctional magnetic Fe3O4 nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance. Yet, many advances in operative surgery do not result from RCTs and many controversies remain without an RCT being conducted.

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Elective high-frequency oscillatory ventilation (HFOV) in preterm infants is known to be as effective as conventional ventilation in the prevention of bronchopulmonary dysplasia without the risk of increased mortality or brain damage. Apparently the defective responses of old mice were not intrinsic to their erythropoietic stem cells.

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After 2 months, computed tomography (CT) showed a reduction in the multiple liver metastases. Evaluation of post-bronchoscopy sputum smears is helpful for earlier diagnosis of pulmonary TB and is an inexpensive and accessible assay. The spina bifida/anencephaly complex in man in some ways resembles the effects of T-locus mutants in the mouse.

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Hospitalists at a community-based teaching hospital documented substantial efforts to communicate with dying patients and their families, which may have resulted in improved end-of-life care. Hyperhomocysteinemia (hyper-Hcy) is an important and reversible cardiovascular disease risk factor. Treatment of supra and intercondylar femoral fractures with a GSH nail parenting style (low warmth), caregiver mental health status and sleep quality at baseline. The remaining 12 rats comprised the control group without irradiation.

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Validation of a combined corneal topographer and aberrometer based on Shack-Hartmann wave-front sensing. Multichannel magnetic stimulation system design considering mutual couplings among the stimulation coils.

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Cardiovascular phenotype of nonalcoholic fatty liver disease: hanging the paradigm about the role of distant toxic fat accumulation on vascular disease. We noticed strong areas of adhesion with orbital bones located at the lacrimal gland, the orbital trochlea and the inferior orbital fissure.

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These fragments were ligated with T vectors, screened through the blue-white screening system to establish cDNA library. Advances in the treatment of metastatic melanoma: new immunomodulatory agents. Eighty-seven anxious children, 140 non-anxious children, and 98 non-anxious adults rated their emotional reactions to an fMRI scan. We suggest that iron may be one of several factors that cause an increase of MMP-9, which is necessary for the development and progression of HNSCC.