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We performed time-resolved autofluorescence measurements on fundus samples from a donor with significant extramacular drusen. Focused optogenetic stimulation of the lateral orbitofrontal cortex and its terminals in the striatum restored the behavioral response inhibition, restored the defective down-regulation, and compensated for impaired fast-spiking neuron striatal microcircuits.

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Red cell units harvested with blood cell separators have an average estimated mean cell age of 30 days, compared to 60 days for unfractionated blood. Validation of a clinical algorithm to diagnose stress urinary incontinence for large studies. Total mesorectal excision for rectal cancer: laparoscopic versus open approach. Only few studies with low quality of evidence addressed these topics. Prediction of soft-tissue outline shape from skeletal remains is useful in forensics and archaeology.

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This study investigated learning, in normal-hearing adults, associated with training (i.e. Our findings provide novel insight into the regulatory complexity of how ubiquitylation and SUMOylation cooperate to orchestrate protein interactions with DSB repair foci.