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Cryofaxol (Cyclophosphamide)

Cryofaxol is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cryofaxol is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin). It belongs to the group of cancer medicines called alkylating agents.

Cryofaxol is also used for some kinds of kidney disease.

Cryofaxol interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by Cryofaxol, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with Cryofaxol, you and your doctor should talk about the benefits of this medicine as well as the risks of using it.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Capsule
  • Powder for Solution
  • Tablet

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Teratogenic activity of the antiepileptic drugs phenobarbital, phenytoin, and primidone in mice. Immune activation in HIV-infected aging women on antiretrovirals--implications for age-associated comorbidities: a cross-sectional pilot study. Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment. Frameshift suppression with L-homoglutamine (hGln) does not significantly affect protein yields or cell growth rates and is mutually orthogonal with amber suppression, permitting the simultaneous incorporation of two unnatural amino acids, hGln and O-methyl-L-tyrosine, at distinct positions within myoglobin. The acute toxicities of waterborne Cd, Cu, Pb, Ni, and Zn were determined in the first-instar larvae (generally considered to be the most sensitive) of Chironomus riparius, under standardized conditions.

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The impact of biodiesel on pollutant emissions and public health. However, we found no superiority of the mobile-bearing total knee prosthesis over the fixed-bearing total knee prosthesis. Radioactive iodine for thyrotoxicosis in childhood and adolescence: treatment and outcomes. Action of instantaneous-delayed action phenformin, alone or in combined therapy, in 50 hospitalized diabetics

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Parallel increased level of galectin-3 with the number of MDSCs in vivo was detected after cisplatin treatment. Magnetic resonance imaging (MRI) allows non-invasive assessment of fetus brain maturation at the beginning of the third trimester because of its high sensitivity for fat and water content changes accompanying the myelin formation. Although early mortality has been substantially reduced and the rate of long-term survival has improved, sCHD is, after preterm birth, the second most frequent cause of neonatal infant death. Synthesis of multiple Pseudomonas aeruginosa biofilm matrix exopolysaccharides is post-transcriptionally regulated.

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Exposure of the islets from spiny mice to a high glucose concentration, concomittantly to vincristine, caused a further reduction in vincristine-induced crystals content of the B-cell. Abnormal QT interval variability in patients with hypertrophic cardiomyopathy: can syncope be predicted? A novel experience in living donor renal transplantation: voluntary exchange kidney transplantation.

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Due to limited data, a comparison of third-generation iron preparations with previous preparations is not possible. Does X-Y pairing during male meiosis protect the paired region of the X chromosome from subsequent X-inactivation? Toxicological characterization of the new water cleaning product and its waste by-product. Trematodes were recovered from esophagus, stomach, and small intestine of the host. To be included, the scale needed to have at least one study, published in a peer-reviewed journal, which examined its psychometric properties with a sample of individuals with SCI.

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Although QT interval was modestly prolonged with NIF, no life-threatening ventricular arrhythmia (i.e., torsades de pointes) occurred. In such patients, if cryptococcal antigen is present in the CSF in a titer of larger than or equal to 1:8, antifungal therapy should be initiated, pending results of other diagnostic studies.

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Data were obtained from a nationally representative sample of 342 men and 525 women aged 65 and over collected during the 2001 National Health and Nutrition Examination Survey. A low functional status appeared as a common factor for ESBLE and MRSA carriage. Results from several groups suggested that placing multiple stents for months to years could dilate the stricture permanently and thus also treat patients with postoperative biliary strictures palliatively.

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PET/CT with sodium 18F-fluoride for management of patients with prostate cancer. Hydroxymethylfurfural and furfural can be estimated automatically at 60 samples/h in a continuous-flow system. Ionic liquid-assisted preparation of laccase-based biocathodes with improved biocompatibility.

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The posterior fibres may be an exception in hyperextension, probably being loaded either because of posterior femoral lift-off or because of the forward curvature of the PCL. Bone marrow cells can be aspirated from patients with malignant disorders, stored at low temperatures, and reinfused into the same patient at a later date. Permanent magnets for the fixation of intracardial pacemaker probes As expected, larger proteins and smaller pore sizes resulted in smaller diffusion coefficients.

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The data show that the CPG can maintain the period and phase of locomotor oscillations both during spontaneous deletions of motoneuron activity and during sensory stimulation affecting motoneuron activity throughout the limb. In support, increased PTEN protein expression was detected in corresponding tissue specimens. In terms of existing formal EMS, there is a need for increased and more regular funding, integration and coordination among existing services, and improved organization and leadership, as could be accomplished by making EMS administration and leadership a more desirable career path. Temporomandibular joint, its development and importance in orthodontic therapy

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Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. The most likely mechanism for the suppression of immune responses by helminths is the release of helminth-derived immunomodulatory molecules. The PK and safety profiles of zibotentan determined in this Chinese patient population are similar to those previously reported. Overall, the replication-competent retrovirus XMRV, present in a high number of laboratories, is able to infect human lymphoid tissue and produce infectious viruses, even though they were unable to establish a new infection in fresh tonsillar tissue.

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Screening genomes of Gram-positive bacteria for double-glycine-motif-containing peptides. To establish whether early mobilisation (less than four weeks after symptom onset) compared with delayed mobilisation (defined as patients staying in bed for at least four weeks after symptom onset) in patients with aneurysmal subarachnoid haemorrhage (SAH), who have not had or could not have any surgical treatment for the aneurysm, will increase the proportion of deaths from rebleeding. On global energy scenario, dye-sensitized solar cells and the promise of nanotechnology. This study aimed to evaluate the prognostic value of coagulation/fibrinolytic activities in breast cancer (BC).

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Anorexic behavior and elevation of hypothalamic malonyl-CoA in socially defeated rats. Dapagliflozin treatment reduced the TmG and splay in both groups. We evaluated the efficacy of YM155, a selective suppressant of survivin, in combination with gemcitabine in the pancreatic cancer cell line MiaPaCa-2.

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A retained sponge is a complication of vacuum-assisted closure therapy. She underwent a second course of chemotherapy with saw her through another two years of disease free period. Patients with well to moderately differentiated T1 tumors may undergo excision if it can be accomplished without compromising the sphincter.

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AoCLF was defined according to the Asian Pacific Association for the Study of the Liver criteria. We show that all three phase II enzymes are present and highly active in skin as compared to phase I.

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The increase of immune cell activity in the prevention of cancer by LAB consumption has also been described. Protracted lymph flow as a complication of kidney transplantation The identification of a murderer and the eventual conviction was largely due to forensic dentistry and in particular the use of bite marks on the victim compared with casts of the teeth of the accused. For accurate needle positioning, in-bore-operated robotic systems have been developed and optimal use of the confined in-bore space become a critical engineering challenge. NADPH oxidases are a family of oxidases that utilize molecular oxygen to generate hydrogen peroxide and superoxide, thus indicating physiological functions of these highly reactive and short-lived species.

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Furthermore, hemocyanin-specific immune T cells were able to suppress the DTH induced to HRBC, provided these two antigens were coupled together. We evaluated seventynine cases of extrahepatic bile duct cancer who had received curative resection in Severence Hospital, Yonsei University from March 1986 to October 2005. In AIDS patients, during intestinal tuberculosis, massive enteric-hemorrhage suggests for involvement of mesenteric arteries by mycobacterium tuberculosis. Three of the women also became involved in a further related research project which led to an editorial publication from the patient perspective and also participated, along with two lead researchers, in the evaluation of the process and outcomes.

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The care of neurasthenic patients and its relation to social insurance Twenty-three patients had a single lesion, while two patients had 3 and 6 lesions, respectively. It is suggested that similarity between the antigenic structure of the cell membrane of the T- and B-lymphocytes, aiding their physical contact, increased the action efficiency of the T-mediator on the B-cell. Fluorescence techniques in analysis of protein-ligand interactions. The analysis included both raw and age-adjusted normed data for multiple choice responses on the D-KEFS Proverbs Test using independent samples t-tests.

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Inhibition of lipid signaling enzyme diacylglycerol kinase epsilon attenuates mutant huntingtin toxicity. To evaluate the complications of ureterorenoscopy (URS) using the modified Clavien classification system for ureteral stones with different localizations.

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Measurement of myeloperoxidase activity in the muscles of mice infected with Trichinella pseudospiralis, T. We synthesized articles making reference to this question, notably those written by Bornstein, author who refers to the dependent personality. In particular, it is a major target for auto-antibodies in experimental autoimmune encephalomyelitis (EAE), which mimics many aspects of multiple sclerosis (MS). The regulation of matrix gamma-carboxyglutamic acid protein (MGP) expression during the process of lung branching morphogenesis and development was investigated.

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Trends from an HIV seroprevalence study among childbearing women in New York State from 1988 through 2000: a valuable epidemiologic tool. Species and age determination of central nervous system tissue by fatty acid patterns. The short life tracers permit the use of high activities and so allow to follow with a good statistic accuracy fast phenomenons such as the different phases of cardiac revolution. Upregulation of prostaglandin receptor EP1 expression involves its association with cyclooxygenase-2.

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Is a day hospital rehabilitation programme associated with reduction of handicap in stroke patients? Psychovegetative disturbances predominated during attacks of atrial fibrillation and because of that PVI was less than zero. We describe a woman who presented with progressive bilateral leg pain, numbness, and gait difficulties. This study was performed to investigate the anti-wrinkle effects of topical applications of green tea extract exhibiting high antioxidant activity after tannase treatment.

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Toward a more comprehensive theory of capacity limits, we examined models of forced-choice recognition of words within printed lists, using materials designed to produce multiword chunks in memory (e.g., leather brief case). The Dlg4/Psd95 scaffold protein and additional signalling proteins, including protein phosphatases, were revealed by STRING analysis as potential players in the altered synaptic function of FDD(KI) mice.

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Although genetic material itself provides a natural data storage medium, tools that allow researchers to reliably and reversibly write information to DNA in vivo are lacking. This retrospective study included 174 renal allograft recipients who were divided into two groups: group A including patients who received perioperative prophylactic antibiotics and group B, who did not receive them.

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Can a trial of motivational lifestyle counseling be effective for controlling childhood obesity and the associated cardiometabolic risk factors? Analysis of nitric oxide signaling functions in tobacco cells challenged by the elicitor cryptogein. Fourteen patients with clinical and histological evidence of mycosis fungoides have undergone a series of immunological tests.

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Sensation seeking status also modulated the FN400 ERP component indexing familiarity and conceptual learning, along with fMRI responses in the caudate nucleus, which correlated with FN400 activity. Reported herein is the formation of hydrogel micropatterns on catalytic surfaces. Synthesis and optimization of a novel series of HCV NS3 protease inhibitors: 4-arylproline analogs. Neoadjuvant chemotherapy (NAC) is routinely used in locally advanced breast cancer, but is increasingly used in early stage patients.

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This Concept article focuses on the potential of DCC to impact and modulate the biological and chemical properties of mixtures of bioactive volatile compounds to gain a more fundamental understanding of the properties of compound mixtures in molecular recognition. Four layer SIS undergoes contracture and calcification when used to cover defects in the tunica albuginea. Data are from the baseline evaluation of 354 individuals enrolled in the ilSIRENTE Study. This model is able not only to predict the outcomes of high-throughput growth phenotyping and gene expression experiments, but also to indicate knowledge gaps and identify previously unknown components and interactions in the regulatory and metabolic networks. In this study, we show that the subcellular localization and functions of 9 and 15 kDa granulysin are largely distinct.

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The adaptor protein CARD9 coordinates Th17- and innate lymphoid cell-mediated intestinal immune responses after epithelial injury in mice. The work deals with the identification of the main mechanisms of hydrocephalus development in patients with parasagittal meningiomas who, besides the additional volume in the cranial cavity, have some degree of venous drainage disorders as a rule. Common theories explain this permeabilization by formation of pores in the lipid bilayer.

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The prevalence of Chlamydia trachomatis infection in Australia: a systematic review and meta-analysis. To review the evidence for the clinical impact of aripiprazole in the treatment of patients with schizophrenia.

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To investigate the feasibility of using noninvasive EEG source imaging approach to image continuous seizure activity in pediatric epilepsy patients. Automated localization of multiple acetylations on Histone H4 was also accomplished on an LC time scale from a complex protein mixture. Epifluorescence and scanning electron microscopic studies supported the better performance of the FA specimen. Some salt-responsive genes were identified to function in metabolism, photosynthesis, stress and defense, energy, protein synthesis and protein degradation.

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Angiotensin-(1-7) attenuates diabetic nephropathy in Zucker diabetic fatty rats. In the present investigation, we show by analysis of the accumulated cytogenetic data on testicular germ cell tumors and computer simulations that two distinct processes are operating in the karyotypic evolution of these tumors. The need for better tolerated antihypertensives had led to development of many new antihypertensives.

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Pain and satisfaction scores were measured by visual analog scale. Hematopoietic progenitor cell lines with myeloid and lymphoid potential. We demonstrated for the first time that exposure to low-dose MeHg during development induces the dysfunction of motor coordination due to changes of synaptic homeostasis in cerebellar granule cells. Current techniques to evaluate the efficacy of potential treatments for airways diseases in preclinical models are generally invasive and terminal.

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Case of temporary paralysis of the oculomotor nerve during local anesthesia at the level of the pituitary Major involvement of adipokines in joint metabolism was not identified. But in DMY, the opposite is observed and the DM domain is likely under positive Darwinian selection. All were significantly less frequent with pemetrexed versus other alternative therapies, except for liver toxicity. The present review summarizes the neurological involvement in connective tissue diseases and highlights does liquid omeprazole need refrigerated trucks recent findings on the diagnosis of neurological manifestations and potential underlying mechanisms.

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Effects of calcining temperature on photocatalytic activity of Fe-doped sulfated titania. The appropriate physiological response torvalipin tabletki cena vs lesnar to changing photoperiod in mammals requires retinal detection of light and pineal secretion of melatonin, but extraretinal detection of light occurs in birds. Additionally, strong positive associations between chemokine immunolabelling and perivascular cuffing and, to a lesser extent, virus antigen score were also observed. Cisapride given as bolus injections (10(-10)-3x10(-5) mol/l) produced dose-dependent dilatations.

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The domestic and foreign research progress in determining the lignin, cellulose and hemi-cellulose content in woody plant ( wood and bamboo used as papermaking raw materials and wood served as potential biomass energy) and herbaceous plant (forage grass and energy grass) by near infrared clariva complete soybean treatment label reflectance spectroscopy technology is comprehensively summarized and the advances in method studies of measuring the composition of lignocelluloses by near infrared reflectance spectroscopy technology are summed up in three aspects, sample preparation, spectral data pretreatment and wavelength selection methods, and chemometric analysis respectively. Night myopia is a correctable cause of decreased visual acuity under conditions of decreased illumination. EPO neuroprotection followed a bell-shaped dose-response curve in vitro and in vivo, whereas toxic EPO effects were never observed, even at high concentrations.

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The nomenclature proposed in the October 2003 report of the Nomenclature Review Committee of the World Allergy Organization is an update of the European Academy of Allergology and Clinical Immunology Revised Nomenclature for Allergy Position Statement published in 2001. A scoring strategy combining statistics and functional genomics supports a possible role for common polygenic variation in autism. To investigate the hemostatic capability of mono- and bipolar transurethral resection of the prostate (TURP) by comparing the microvessel diameter of hyperplastic prostate with the coagulation depth achieved with topiramate 25 milligram tablets android mono- and bipolar TURP. Dietary fish oil may modulate the membrane excitability and is a possible strategy for preventing the impairments of diabetes on hippocampal function.