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Sortiva (Losartan)
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Losartan

Sortiva is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure may reduce the risk of strokes and heart attacks.

Sortiva is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Sortiva relaxes the blood vessels. A lower blood pressure will increase the supply of the blood and oxygen to the heart.

Sortiva is also used to decrease the risk of stroke in patients with high blood pressure and enlargement of the heart. It is also used to treat kidney problems in patients with type 2 diabetes and a history of hypertension.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

Other names for this medication:
Losartan, Cozaar, Lortaan, Losacar, Losakind, Lostat, Omnitan, Losium, Angilock, Angizaar, Aratan, Araten, Cardon, Cartan, Cormac, Corodin, Corus, Cosart, Covance, Eklips, Etan, Fensartan, Fortzaar, Hilos, Lacine, Lara, Larb, Lavestra, Lifezar, Loben, Logika, Loortan, Lopo, Lorista, Losa, Losacor, Losan, Losap, Losaprex, Losar, Losart, Losartanum, Losartas, Losatan, Losatrix, Lostan, Lotan, Lotar, Lotim, Lozap, Lozar, Lyosan, Mozartan, Niten, Normatens, Ocsaar, Osartil, Ostan, Prelow, Prosan, Rasertan, Rasoltan, Repace, Resilo, Rosatan, Sarilen, Sarlo, Sarvas, Sarve, Simperten, Sortal, Sortiva, Tacardia, Tozaar, Xartan, Zaart, Zartan,

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These data will elucidate the neuroplasticity of ADSCs and provide a new protocol for in vivo tracking of stem cells that are seeded to repair injured peripheral nerves. Over the past several years much has been learned about how the intimate contacts made between proteins and DNA enable proteins to recognize and bind with high specificity only to their cognate DNA binding sites. Osteoprotegerin levels are increased in patients with venous thromboembolic disease. Biological variation of lactate dehydrogenase isoenzyme-1/isoenzyme-2 ratio. It is concluded that peroperative pancreatic needle biopsy is a safe procedure which is easily performed without special instruments.

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Irregular location of major pectoral muscle can be a causative factor of pectus excavatum. Ongoing research in the fields of process engineering, surface chemistry and protein chemistry can help to close this gap. The effect of MCFA on an intestinal nematode (Nematodirus sp.) was therefore evaluated in four calves (4 to 11 month old). Therapeutic targets have been defined for diseases like diabetes, hypertension or rheumatoid arthritis and adhering to them has improved outcomes.

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Hierarchical clustering and principal component analyses confirmed that counteraction of PTHrP in GCT stromal cells results in a clear-cut gene expression pattern distinct from all other treatment groups and the control cell line human fetal osteoblast (hFOB). The GRADE and the GRADE-RAND methods were utilised to develop recommendations. Mono- and bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: evidence for conformational peculiarity of the sulfated iduronate residue.

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Delayed graft function: risk factors and the effects of early function and graft survival. After a healing period of 6 months, the mandibles were removed en bloc for micro-CT and histologic analyses.

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The pharmacokinetics in normal mice and vascular permeability of the PEG-HSA in a lipopolysaccharide-induced acute lung injury mice model were evaluated. Possible mechanisms of the barbiturate effect in the retina are discussed. Report of the congress on tuberculosis in the German Democratic Republic in Leipzig To observe changes of serum Th1/Th2 cytokines and IgE of rats with experimental allergic rhinitis (AR) treating with Scoparone (20 ml/kg, the concentration is 168 mg/L).

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Strain to strain differences, especially in coat color can make it difficult to determine the stage of the estrous cycle accurately by visual observation. Antagonistic modulation of gliomagenesis by Pax6 and Olig2 in PDGF-induced oligodendroglioma.

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The importance of this ubiquitous organelle for human health is highlighted by the fact that PBDs are multisystemic disorders that often cause death in early infancy. The functions of WHIRLY1 and REDOX-RESPONSIVE TRANSCRIPTION FACTOR 1 in cross tolerance responses in plants: a hypothesis. After admission the diagnosis was confirmed by the examination of periferal blood, cytologic and histologic examination of the bone marrow and after a subsequent examination of the spleen tissue. Perfluorononanoic, perfluorodecanoic, perfluoroundecanoic, and perfluorododecanoic acids were found sporadically in the liver tissue of the Blokkersdijk mice.

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Such compounds have proven to act through the inhibition of the gp120-CD4 protein-protein interaction that occurs at the very early stage of the HIV-1 entry process. Speciality consultation was achieved by means of teleophthalmology during which images were converted to Digital Imaging and Communications in Medicine standard and transferred to the base hospital by a satellite link using a very small aperture terminal at 256-384 kilobits per second with store-and-forward technology as well as real-time videoconferencing when possible.

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Prophylactic strategies have decreased the rate of CMV infection/disease among SOT. Of the five subjects who received 24 live treatments, four appeared to be able to fall asleep with little difficulty and to awake feeling moderately to very well rested.

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The aim of this study is to further identify the risk loci in the MHC region for ESCC in Chinese population. Measurement of motion resulted in an increase during the first hour in the presence of theogallin and L-theanine. Fifteen healthy young participants of both sexes (aged 26-42 years) volunteered for this study.

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MHC associations with clinical and autoantibody manifestations in European SLE. Taken together, these results suggest that the brainstem and the cortex initially progress through a phase of developmental recapitulation prior to the onset of NMDA mediated adult somatosensory reorganization.

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These data suggest that autophagy contributes to exacerbated brain injury in diabetic condition, and autophagy-mediated cell death may be a therapeutic target in diabetic stroke. The existence of comparable Wnt gradients in the vertebrate spinal cord could reflect similar roles for Wnt signaling in vertebrate motor circuit assembly. The experimental value of characteristic adsorption energy was computed by modeling the isotherm equilibrium data (which contain 120 isotherms involving five VOCs and eight activated carbons at 293, 313, 333, and 353 K) with the Gauss-Newton method in a statistical package R-STAT. We sought to determine the incidence of erectile dysfunction following pelvic fracture urethral injuries in children, and to identify the related causes and risk factors.

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Complementary and alternative medicine education for medical profession: systematic review. Melittin, one of the most important bioactive peptides, has been isolated and characterized in A. Pain intensity with visual analog scale (VAS), the number of tender points, the fibromyalgia impact questionnaire (FIQ), the Beck depression inventory (BDI) were evaluated.

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Although a higher signal to noise ratio (SNR) reached to near shot noise limited SNR is attained by attaching a resonator to the photodetector for pulse repetition, the electrical bias cannot compensate for the optical balance. Social marketing uses marketing techniques to achieve a social or healthy goal, and can be used in alcohol education. Direct experimental evidence of the effects of dust particles on the fluctuations of a low collisionality plasma is reported, in agreement with the expectations of kinetic theory. Rocuronium and sugammadex used effectively for electroconvulsive therapy in a patient with Brugada syndrome.

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The 2009 influenza pandemic highlighted the need to develop alternate assays that are able to rapidly quantitate HA antigen for vaccine formulation. Rapidly progressive behavioral changes and parkinsonism in a 68-year-old man. Investigations on the adaptivity of dermatophytes to griseofulvin. We further show that unlike cells from wild-type mice, Booreana cells transduced with AML1-ETO9a or MLL-AF9 retroviruses fail to generate leukemia upon transplantation into irradiated recipients.

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The results support the possibility that a classical conditioning paradigm applied to the spinal cord can induce alterations in spinal reflexes of long duration. The proximal segment of some terminal arterioles was innervated by one or two axons which were observed to diverge from the vessels and terminate in the tissue.

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We use an intubating laryngeal mask (ILM) in preference to an endotracheal tube (ETT) as the ventilatory device during percutaneous dilatational tracheostomy (PDT) to overcome potential problems such as difficult ventilation, accidental extubation, damage of the ETT or of the bronchoscope, and need for additional assistant to secure the airway. Dose escalation study of paclitaxel in combination with fixed-dose irinotecan in patients with advanced non-small cell lung cancer (JCOG 9807). Continuity of the alimentary tract was restored by an abomasoduodenal anastomosis. This article considers the work of a number of contemporary British poets who have attempted to articulate some of the experiences that dementia entails.

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The resulting dimension-specific sequence representations support independent predictions of what will appear next, where it will appear, and how one will have to respond to it. A recent approach has been to develop chemotypes that target PDE-VII, a cAMP-specific PDE, expressed widely in immune and pro-inflammatory cells. Spontaneous remission in a case of severe crescentic IgA nephropathy without long-term treatment. European age standardised rates of self rated general health, for men and women classified by the government social class scheme.

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Yet, little research explores academically-based mathematics instruction for this population. The aim of the present study was therefore to develop and evaluate suitable pharmacokinetic models for the quantification of the cerebral A1AR in high-resolution PET. Ageing and inter-generational wealth flows in two Indonesian communities. The nature of the modifications incorporated was shown to have a drastic effect on inhibition against both the fibrinogenolytic and amidolytic activities of thrombin and thus highlights a potential means for attenuating the biological activity of the protein. Similarly, brefeldin A (BFA) treatment led to a punctate distribution of VP3, scattered throughout the cytoplasm of infected cells.

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This study involved, in a blind comparison of VB and FB, consecutive patients presenting with symptoms or plain chest radiography abnormalities raising the suspicion of pulmonary neoplasm. It has been shown that primary amenorrhea and sterility observed in most of the patients were determined by changes in the ovaries and uterus as a result of a prolonged effect of androgens of adrenal origin.

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Several aminobisphosphonates inhibit cancer cell migration by preventing the activation of Rho through inhibition of the mevalonate pathway. A computerized literature search was conducted on Medline, Science Citation Index, Current Contents, Embase, and PubMed databases for English language publications from the first report of GLS in pregnancy in 1995 to June 2012. We determined the effect of a panel of non-nutritive sweeteners, aspartame, saccharin and acesulfame-K, delivered in doses that would be consumed in normal usage. The design of compounds that selectively inhibit a single kinase is a significant challenge, particularly for compounds that bind to the ATP site.

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Three supervised machine learning methods were employed to construct classifiers. The European Sentinel GP Networks Monitoring End of Life Care (EURO SENTIMELC) study was designed to describe and compare the last months of life of patients dying in different European countries.

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Telangiectatic hyperplastic nodule associated with vascular malformation in a patient with chronic hepatitis B: radiologic and pathologic features. The ears of all animals were prepared for histological study so that the extent of cochlear damage could be determined. To the best of our knowledge, we believe that this location for extra-adrenal myelolipoma has not been previously described in the literature.

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Recent developments in biotechnology now permit the identification of immunologically specific antigens in Treponema pallidum, and cloning of appropriate genetic information in Escherichia coli has led to the production of pure specific reagents. Amino acid transport in peripheral nerve: energy and sodium dependence. The fractionation of frog olfactory preparation by ion-exchange chromatography and gel filtration permitted to obtain fractions capable of making artificial lipid membranes sensitive to odorants, such as camphora, musc ambrette and linalool.

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Poly(4-vinylpyridine) supported acidic ionic liquid: a novel solid catalyst for the efficient synthesis of 2,3-dihydroquinazolin-4(1H)-ones under ultrasonic irradiation. The physiological status of pregnancy resulted in a higher DM intake but lower measures of fat depth and eye muscle depth, and suckling led to an increase in DM intake but a reduction in body weight and fat score through mobilisation of fat and muscle reserves. The active center aspartyl residue, which reacts with 1,2-epoxy-3-(p-nitrophenoxy)propane (Chen, K. Furthermore, there was no consumption of quinine solution before and after the lesion.

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T2-weighted CMR depicts infarct-related myocardial edema as a marker of acute but not chronic myocardial injury. Regardless of the route of application, a certain amount of nontumorous liver parenchyma will be collaterally damaged by radiation.

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A 38-year old patient with previously untreated HIV infection presented with progressive cephalgia, photophobia, polydpsia and nausea/vomiting. Transmissible spongiform encephalopathies (TSE) arise as a consequence of infection of the central nervous system by prions and are incurable. At about 6 days after primary immunization of CBA or C3H mice with BALB/c spleen cells, suppressive antibodies can be measured in the sera of the animals. The electrocardiographic changes in the dog preparation were virtually identical to those in the patients and strongly correlated with a fall in myocardial conduction velocity. One of these methods, taurolidine lock, has shown some potential in several studies, but it has been studied primarily in patients with a relatively high CRBSI rate.

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Both types of bacteria are transovarially transmitted from one generation to the next. A phenomenology of problematic sexual behavior occurring in sleep.

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Most frequent are intoxications with acetaminophen, viral hepatitis, or liver damage of unknown origin. Ca, Pi and CPP could be useful additional variables in determining risk in CHF patients. Lastly, in the post-screen stages, the ligand screening data is processed and analyzed using various strategies, and the resulting preliminary hits are subjected to a series of secondary and tertiary assays to eliminate false positives and poor quality hits. Patients with spinal cord injury, their caregivers and health-care personal should be aware of this complication of spinal cord injury, in order to prevent and treat autonomic dysreflexia properly and avoid potentially fatal episodes.

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Consistent with these in vitro findings, cardiomyocyte-specific inhibition of FGF signaling in adult mice demonstrated mislocalization of Cx43 at intercalated discs, whereas localization of N-cadherin and desmoplakin was not affected. Controlled evaluations of the effectiveness of financial incentive interventions, compared to no intervention or usual care, to encourage healthy behaviour change, in non-clinical adult populations, living in high-income countries, were included. Impact of nurse integrated rounds on self-reported comprehension, attitudes, and practices of nurses and resident physicians in a pediatric intensive care unit.

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Light and electron microscopy findings in early and late stages of heart failure. Migration and invasion of FLSs in vitro were measured by the Boyden chamber assay. Since non-traditional flours or other derivatives could contain relatively high amounts of antinutritional factors that also have health implications, related information about this subject is included.

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Down regulation plus HRT standardized surface appearance but tissue response is significantly different from the natural cycle, natural cycle plus HRT or menopause plus HRT. The midline distortion of anterior skull base should be considered to be spontaneously corrected during the follow-up periods in patients with all types of UFP who underwent FOA, unlike posterior skull base in the patients with grades 2B and 3 classification. To study the trends we analysed the pattern of new drug approvals and introductions in India over the past 15 years (1988-2002). Significant immunoreactivity was noted in glioblastoma (12 of 20), pleomorphic xanthoastrocytoma (6 of 10), ganglioglioma (8 of 10), meningioma (14 of 20), and hemangioblastoma (10 of 10). The HIV-1-containing macrophage compartment: a perfect cellular niche?

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The direct cardiac action of 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF) was studied in isolated perfused guinea-pig heart preparations. The location, reasons for defects, and the number of cases have been also described. We present a case of a large submucosal mass excised endoscopically, resulting in a large perforation that was closed using endoclips. Collectively, these results suggest that the cytostatic effect of 2-ME(2) may be mediated through the prevention of the translocation of beta-catenin to the nucleus parallel with an increase in cell-cell adhesion by increasing membrane beta-catenin production, eventually preventing cell migration.

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